Cheminformatics & Gromacs Lab - Malaysia
Cutting edge technology in drug discovery and cancer therapeutics
Princple adviser and designer of drug discovery projects

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Parham Jabbarzadeh Kaboli (academic name: Parham J. Kaboli) in brief:

Parham Jabbarzadeh Kaboli in brief:

- A research leader in cancer discovery and cell signaling
- An experienced lecturer in cell and molecular biology
- An associate member of the American Association of Cancer Research (AACR)
- A member of the American Society for Pharmacology and Experimental Therapeutics (ASPET)
- A member of the American Association for Advancement of Science (AAAS)

Parham Jabbarzadeh Kaboli in detailed:

I am strongly interested in systems biology, cell signaling, and using computational solutions to find the best promising therapeutics for cancer. I previously worked as university lecturer and laboratory manager for a couple of years, then started my PhD at Univerisiti Putra Malaysia (UPM) in molecular medicine (2013-2017).

Research capabilities:

(1) In vitro cellular approach - Protein detection techniques and verifying drug candidates in cancer treatment
(2) In silico approach - Target detection, target optimization, and Virtual High-Throughput Screening

Teaching capabilities:

(1) Cell and molecular biology
(2) Biochemistry
(3) Pharmacology


In addition to my research activities, I am delivering my expertise to the next generation of researchers. Since 2014, therefore, I have established a group of young researchers and teaching them how to perform a modelling and drug discovery project.

I am currently analyzing protein/ligand interactions, based on computational and experimental methods. I am the author of two books and several ISI articles.

The list of my publication is available on my official website (current website), and my ResearchGate and Google Scholar profiles.

Contact information:



This is a bilingual (English/Persian) item.

As we have some colleagues or students who are registering in our courses or services, we officially publish this guideline written by Dr Ramin Sadeghi, associate professor of Mashhad University of Medical Sciences. We strictly follow this guideline in our current or future collaborations.

با توجه به اینکه دوستانی چه از میان اعضای هیات علمی و چه از میان دانشجویان، در پروژه ها، کارگاه ها و خدمات آموزشی ما در حوزه طراحی دارو ثبت نام می کنند ، دستورالعمل درج نام نویسنده که توسط آقای دکتر رامین صادقی، دانشیار دانشگاه علوم پزشکی مشهد، تدوین شده است، بطور رسمی به عنوان دستورالعمل برای تمام پروژه ها و همکاری های آینده قرار می گیرد. لطفا دوستانی که تمایل به تعامل فی ما بین دارند، قبلا این اصول را مطالعه بفرمایند.

ما برای در نظر گرفتن همکاران مان بر روی مقالات مشترک بطور سختگیرانه ای از این اصول تبعیت می کنیم.

چه کسی نویسنده یک مقاله علمی تلقی میشود؟ ملاکهای گنجاندن یک نفر به عنوان نویسنده یک مقاله علمی چیست؟

In the current post, we have explained in detail the criteria of authorship, order of authors, and responsibility of authors according to the accepted international guidelines.

در این پست، ما به تفصیل در مورد ملاکهای نویسندگی، ترتیب نویسندگان، و مسوولیت هر یک از نویسندگان بر اساس گایدلانهای معتبر جهانی بحث خواهیم کرد.

Why authorship is important?

In the scholarly world, authorship is the basis of rewards and career advancement. Grant allocation is usually based on the previous authorship records. Career advancement (for example promotion to associate professor or full professor) is highly dependent on number and quality of the authored material. This is the reason that, authorship is very important in the scholarly arena and there are many legal disputes in this regard.

در دنیای علم، نویسنده بودن مبنای پیشرقت در حرفه دانشگاهی به حساب میرود. اختصاص بودجه و جذب منابع و نیز ارتقا در سمت دانشگاهی بسیار وابسته به تعداد و کیفیت مطالب چاپ شده توسط افراد است. به همین علت، مساله معیارهای نویسندگی در جهان علم بسیار مهم بوده و منشا بسیاری از اختلافات حقوقی می باشد.

Author watson Home 20:51:25 | | | printer friendly | | create pdf of this news item

Each weekend, you are linked to the best article that , during each week, I have read and found it great in the field of Cancer and Pharmacology. I try to encourage the fellow researchers and post-graduate students to read so much as they can about new therapeutics.

Weekend Recipe for February 2016 - the fourth week

The birth of modern chemotherapy

This paper published in the Pharmacologist is very interesting showing you how chemotherapy has been evolved as a tool to treat cancer.

Download this recipe

To download other weekend recipes click here.
Author watson Home 23:41:31 | | | printer friendly | | create pdf of this news item

Each weekend, you are linked to the best article that , during each week, I have read and found it great in the field of Cancer and Pharmacology. I try to encourage the fellow researchers and post-graduate students to read so much as they can about new therapeutics.

Weekend Recipe for February 2016 - the second week

The impact of molecular dynamics on drug design: applications for the characterization of ligand– macromolecule complexes

This week I would like to suggest this paper. This paper is very great review paper which is useful for those are interested in drug discovery and are got a little bit confused.

Abstract——Among all tools available to design new drugs, molecular dynamics (MD) simulations have become an essential technique. Initially developed to investigate molecular models with a limited number of atoms, computers now enable investigations of large macromolecular systems with a simulation time reaching the microsecond range.

The reviewed articles cover four years of research to give an overview on the actual impact of MD on the current medicinal chemistry landscape with a particular emphasis on studies of ligand–protein interactions. With a special focus on studies combining computational approaches with data gained from other techniques, this review shows how deeply embedded MD simulations are in drug design strategies and articulates what the future of this technique could be.

Download this recipe

If interested in the field of drug discovery I would also like to suggest these articles. These are well-written too.

To download other weekend recipes click here.

Author watson Home 15:38:45 | | | printer friendly | | create pdf of this news item

Each weekend, you are linked to the best article that , during each week, I have read and found it great in the field of Cancer and Pharmacology. I try to encourage the fellow researchers and post-graduate students to read so much as they can about new therapeutics.

Weekend Recipe for February 2016 - the first week

Ligand efficiency indices for effective drug discovery

This week I would like to suggest this paper. This paper written by Prof. Cele Abad-Zapatero help me a lot to make new insights in drug discovery in my projects. The paper is incredibly insightful and provide new indices to better understanding of drug/target interaction.

Abstract——Successful drug discovery requires the optimization of a large number of variables ranging from strictly physicochemical parameters such as molecular weight to more complex parameters related to toxicity and bioavailability. Presently, structure-based methodologies influence many aspects of the drug discovery process from lead discovery to the final preclinical characterization. However, critical biological issues along the path to the market have diminished the impact and power of this methodology. The physicochemical properties of the novel chemical entities designed and guided by structural methods have become the subject of intense scrutiny from lead discovery to drug candidate. The idea of ligand efficiency (binding energy/non-hydrogen atoms) has recently emerged as a useful guide to optimize fragment and lead selection in the discovery process.

More generalized concepts of ligand efficiency, related to efficiency per dalton and per unit of polar surface area, have also been introduced and will be discussed in the broader context. Preliminary results and trends obtained using ligand efficiencies as guides are reviewed and their future application to guide drug discovery will be discussed, as well as their integration into the structure-based drug design methods to make them more effective and numerically robust.

Download this recipe

To download other weekend recipes click here.
Author watson Home 05:23:55 | | | printer friendly | | create pdf of this news item

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Selected journal articles watson @ (19:44:34) (Curriculum Vitae)
Proofreading and Editing Service watson @ (21:55:53) (Services)
The seventh Recipe - February 2016: the third week watson @ (14:29:52) (Weekend Recipe: For further reading)

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Parham Jabbarzadeh Kaboli

Lecturer and Researcher
in Molecular Pharmacology

Expert in:

Cell and molecular Biology
Modelling and drug discovery
Cancer signaling pathways

H-index= 3 (Google Scholar)
i10-index= 3
Overall impact factor= 7.55
Overall citation= 102 (Google Scholar)


The American Society for Pharmacology and Experimental Therapeutics (ASPET)

American Association of Cancer Research (AACR)

American Association for Advancement of Science (AAAS)


Department of Biomedical Science,
Faculty of Medicine and Health Sciences,
Universiti Putra Malaysia,
UPM Serdang 43400,
Selangor, Malaysia

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